Activity

Evaluate the effect of intravenous golimumab on health-related quality of life (HRQoL) in patients with ankylosing spondylitis (AS) through week 28 of the phase III, multicenter, randomized, double-blind, placebo-controlled GO-ALIVE study.

Adult patients (n= 208) were randomized to IV golimumab 2 mg/kg (n= 105) at weeks 0, 4, and 12 and every 8 weeks or placebo (n= 103) at weeks 0, 4, and 12, with crossover to golimumab 2mg/kg at weeks 16, 20, and every 8 weeks. General HRQoL was evaluated using the Short Form Health Survey (SF-36) Physical Component Summary/Mental Component Summary (PCS/MCS), and the EQ VAS, and AS disease-specific HRQoL was assessed using the Ankylosing Spondylitis Quality of Life (ASQoL) instrument.

Mean improvements from baseline in SF-36 PCS were greater in the golimumab group versus the placebo group at weeks 8 and 16 (6.8 vs 2.1 and 8.5 vs 2.9, respectively; P < .001); similar results were observed for SF-36 MCS (5.6 vs 1.7 and 6.5 vs 0.8, respectively; P < .001). Mean improvement in each of 8 subscale scores of the SF-36 were also greater for golimumab-treated patients versus placebo at weeks 8 and 16. Mean improvements in EQ VAS and ASQoL were greater in the golimumab group versus placebo at week 8 and week 16. Greater proportions of golimumab-treated patients had clinically meaningful improvement in SF-36 PCS, SF-36 MCS, EQ VAS, and ASQoL at weeks 8 and 16; improvements in SF-36 PCS/MCS, EQ VAS, and ASQoL were maintained through week28.

Golimumab-treated patients had greater mean improvements in HRQoL measures compared with placebo through week 16. Clinically meaningful improvements were observed as early as week 8 and continued through week28.

Golimumab-treated patients had greater mean improvements in HRQoL measures compared with placebo through week 16. Clinically meaningful improvements were observed as early as week 8 and continued through week 28.

The study was carried out to determine the psychological impact levels of nurses and midwives due to the COVID-19 outbreak.

The research is planned in a descriptive type. Nurses and midwives working in any health institution in Turkey constituted the population of the research. The questionnaire form of the study was shared on social media tools between 01 and 14 April 2020 and a total of 758 nurses and midwives were included in the study sample. Personal Information Form, State-Trait Anxiety Inventory and Intolerance of Uncertainty Scale were used as data collection tools.

Participants who attended the study were 56.9% of nurses and 43.1% of midwives. BP-1-102 ic50 Approximately half of the nurses and midwives (48.8%) participating in our study contacted the patient with suspected COVID-19, and 29.8% provided care to the patient diagnosed with COVID-19. Nurses and midwives were scored 52.75±9.80 for State Anxiety, 44.87±7.92 for Trait Anxiety Inventory and 35.16±9.42 for Intolerance of Uncertainty Scale. It has been determined that 54.5% of nurses and midwives have been making their lives worse since the outbreak started, 62.4% had difficulties in dealing with the uncertain situation in the outbreak, 42.6% wanted psychological support and 11.8% had alienated from their profession. It was determined that there was a difference between scale scores and difficulties in work, family and private life due to COVID-19.

As a result, it is seen that the midwives and nurses in our country have high psychological effects due to the COVID-19 outbreak.

As a result, it is seen that the midwives and nurses in our country have high psychological effects due to the COVID-19 outbreak.

Violence against women (VAM) is still considered a global health problem and is highly prevalent in Turkey. This study aimed to determine the relationship between women’s exposure to spousal/partner violence and their attitudes towards honor, social gender roles, and beating in Turkey.

The study was designed as descriptive and completed with 847 women in Turkey. Data were collected with a questionnaire, the Attitudes towards Honor Scale (AHS), the Attitudes towards Wife-beating Scale (ATWB), and the Gender Roles Attitudes Scale (GRA).

The median age of the women was 34 (18-67) years. It was found that 23% of the women were exposed to physical violence, 46.8% to verbal violence, 33.6% to emotional violence, 21.1% to sexual abuse, and 13% to economic violence. There was a negative relationship between GRA score and ATWB and AHS scores. It was determined that the attitude of an individual towards social gender posed a risk for physical (p = 0.037) and sexual violence (p = 0.037), the attitude towards honor posed a risk for sexual violence (p = 0.002), and that the attitude towards wife-beating posed a risk for all types of violence including physical, verbal, emotional, sexual, and economic violence (p < 0.001).

As women’s egalitarian attitudes towards social gender increased, their approving attitudes towards wife-beating, supervision of women by their family members, and their association with family honor decreased. Community-based interventions that promote egalitarian social gender roles could reduce VAM in this community.

As women’s egalitarian attitudes towards social gender increased, their approving attitudes towards wife-beating, supervision of women by their family members, and their association with family honor decreased. Community-based interventions that promote egalitarian social gender roles could reduce VAM in this community.Inpatient violence is a widespread problem in psychiatric wards and has often serious consequences. Literature indicates that de-escalation techniques are the recommended first-line intervention for managing violence, are widely used to reduce it, and restrictive practices in mental health settings. However, these techniques and models are not used at the optimum frequency and/or important factors are limiting their use and effectiveness. We aimed to determine what kind of de-escalation methods are used to reduce violence and coercion in Finnish psychiatric hospitals. Descriptive qualitative research using semi-structured questionnaires and Framework Analysis was used. The results of the study are reported in quantitative terms. A survey of psychiatric wards (N = 65) in Finland’s hospital districts (n = 16) was conducted in the Autumn of 2019 to find out which de-escalation models are used. Finnish psychiatric wards use both the Safewards and Six Core Strategies models to reduce violence and the use of restrictive practices.