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Colorimetric sensors for the rapid detection of numerous analytes have been widely applied in many fields such as biomedicine, food industry and environmental science due to their highly sensitive and selective response, easy operation and visual identification by naked eyes. In this review, the recent progress of the colorimetric sensors based on the magnetic nanomaterials with unique nanozymes-like catalytic activity (magnetic nanozyme) and their colorimetric sensing applications are presented. Emerging magnetic nanozyme-based colorimetric sensors, such as metal oxide/sulfides-based, metal-based, carbon-based, and aptamer-conjugated magnetic nanomaterials, offer many desirable features for target analytes detection. And due to the unique nanoscale physical-chemical properties, magnetic nanozymes have been used to mimic the catalytic activity of natural enzymes such as peroxidases, oxidases and catalases. This review also highlights the catalytic mechanisms of enzyme-like reactions, and promising colorimetric sensing system for the detection of chemical compounds like H2O2, pesticide, ascorbic acid, dopamine, tetracyclines, perfluorooctane sulfonate, phenolic compounds, heavy metal ion and sulfite have been deeply discussed. In addition, the remaining challenges and future directions in utilizing magnetic nanozyme for colorimetric sensors are addressed.With a growing interest in precise and sensitive diagnosis for criminal investigations, nanoparticles (NPs) have intrigued scientific minds working in the field of forensic science due to their exceptional properties. Magnetic nanoparticles (MNPs) have emerged as a powerful tool for improving forensic analysis due to their super magnetic behavior combined with smaller dimensions. MNP-based applications can benefit criminologists to solve criminal mysteries with greater precision and pace. This review highlights the different types of MNP-based applications and their developmental and implicational aspects of forensic science. It also renders insight into the future prospects of a splendid blend of nanotechnology and forensic science, leading to a better scientific analysis.The determination approaches of Fe (Ⅲ) in biological samples were developed by a novel water-soluble silicon nanoparticles (SiNPs). Selleck Entinostat The SiNPs were synthesized by a facile microwave-assisted method, and simultaneously featured strong blue fluorescence (photoluminescence quantum yield 25.2%), long lifetime (~13.29 ns) and good photo-stability. The fluorescence intensities of SiNPs were gradually quenched with Fe (Ⅲ) concentration increasing from 2.0 to 50 μmol/L. The detection limit of the established method was 0.56 μmol/L and the precision for eleven replicate detections of 20 μmol/L Fe (Ⅲ) was 3.2% (relative standard deviation, RSD). The spiked recoveries were 99.0%-104.5%. Results of the lifetime decay and cyclic voltammetry (CV) evidenced that the electron transfer was responsible for the fluorescence quenching mechanism of SiNPs and Fe (Ⅲ). Moreover, the SiNPs were successfully applied in the determination of Fe(Ⅲ) in different environmental waters and human serum. Finally, the resulting SiNPs exhibited the green fluorescence in HeLa cells as the optical probe.Non-targeted screening (NTS) in mass spectrometry (MS) helps alleviate the shortcoming of targeted analysis such as missing the presence of concerning compounds that are not monitored and its lack of retrospective analysis to subsequently look for new contaminants. Most NTS workflows include high resolution tandem mass spectrometry (HRMS2) and structure annotation with libraries which are still limited. However, in silico combinatorial fragmentation tools that simulate MS2 spectra are available to help close the gap of missing compounds in empirical libraries. Three NTS tools were combined and used to detect and identify unknown contaminants at ultra-trace levels in surface waters in real samples in this qualitative study. Two of them were based on combinatorial fragmentation databases, MetFrag and the Similar Partition Searching algorithm (SPS), and the third, the Global Natural Products Social Networking (GNPS), was an ensemble of empirical databases. The three NTS tools were applied to the analysis of real samples from a local river. A total of 253 contaminants were identified by combining all three tools 209 were assigned a probable structure and 44 were confirmed using reference standards. The two major classes of contaminants observed were pharmaceuticals and consumer product additives. Among the confirmed compounds, octylphenol ethoxylates, denatonium, irbesartan and telmisartan are reported for the first time in surface waters in Canada. The workflow presented in this work uses three highly complementary NTS tools and it is a powerful approach to help identify and strategically select contaminants and their transformation products for subsequent targeted analysis and uncover new trends in surface water contamination.Exposure to colorless ammonia gas may lead to damage in human organs or even death. Herein, we describe facile fabrication of an environmentally-friendly, portable, reversible, and sensitive solid-state colorimetric cellulose (Cell)/anthocyanin (Anth) vapochromic sensor that exhibits instant visual color change to both gaseous and aqueous phases of ammonia. The naturally occurring anthocyanin can be easily extracted from the red-cabbage plant and applied as a direct dyestuff onto viscose fibers in the presence of potassium aluminum sulfate as mordant to generate nanoparticles of mordant/anthocyanin coordinated complex. Thus, upon exposure to aqueous ammonia, an instant color change of the smart (Cell-Anth) diagnostic assays, from purple to colorless, was noted and quantitatively probed via both CIE Lab coordinates and UV-Vis spectral measurements. Importantly, the fabricated (Cell-Anth) viscose fabric showed rapid responses, fraction of second, with a good limit of detection (LOD) in the range of 200-1200 mg L-1. This receptor also demonstrated ratiometric changes in the UV-Vis absorbance spectra, giving a hypsochromic shift from 611 to 375 nm upon increasing the total content of ammonia in an aqueous media. The morphologies of Cell-Anth fabrics as well as particle size of the generated mordant/dye complex on the fabric surface have been characterized by transmission electron microscopic (TEM), scan electron microscopy (SEM), energy-dispersive X-ray patterns (EDX) and Fourier-transform infrared spectroscopic (FT-IR). The comfortability of the dyed cellulose fibers was also investigated in terms of their bend length, air-permeability and colorfastness properties. Significantly, the present study offers a promising onsite vapochromic device that enables detection of ammonia in either aqueous or gas phase in various environments and products.