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By observation of extensive experiments, our approach can preserve the intrinsical information of networks more effectively than the state-of-the-art works on a number of benchmark datasets with very different topological characteristics.The distributed optimal position control problem, which aims to cooperatively drive the networked uncertain nonlinear Euler-Lagrange (EL) systems to an optimal position that minimizes a global cost function, is investigated in this article. In the case without constraints for the positions, a fully distributed optimal position control protocol is first presented by applying adaptive parameter estimation and gain tuning techniques. As the environmental constraints for the positions are considered, we further provide an enhanced optimal control scheme by applying the ε-exact penalty function method. Different from the existing optimal control schemes of networked EL systems, the proposed adaptive control schemes have two merits. First, they are fully distributed in the sense without requiring any global information. Second, the control schemes are designed under the general unbalanced directed communication graphs. The simulations are performed to verify the obtained results.This work estimates the severity of pneumonia in COVID-19 patients and reports the findings of a longitudinal study of disease progression. It presents a deep learning model for simultaneous detection and localization of pneumonia in chest Xray (CXR) images, which is shown to generalize to COVID-19 pneumonia. The localization maps are utilized to calculate a “Pneumonia Ratio” which indicates disease severity. The assessment of disease severity serves to build a temporal disease extent profile for hospitalized patients. To validate the model’s applicability to the patient monitoring task, we developed a validation strategy which involves a synthesis of Digital Reconstructed Radiographs (DRRs – synthetic Xray) from serial CT scans; we then compared the disease progression profiles that were generated from the DRRs to those that were generated from CT volumes.Heterogeneous palmprint recognition has attracted considerable research attention in recent years because it has the potential to greatly improve the recognition performance for personal authentication. check details In this article, we propose a simultaneous heterogeneous palmprint feature learning and encoding method for heterogeneous palmprint recognition. Unlike existing hand-crafted palmprint descriptors that usually extract features from raw pixels and require strong prior knowledge to design them, the proposed method automatically learns the discriminant binary codes from the informative direction convolution difference vectors of palmprint images. Differing from most heterogeneous palmprint descriptors that individually extract palmprint features from each modality, our method jointly learns the discriminant features from heterogeneous palmprint images so that the specific discriminant properties of different modalities can be better exploited. Furthermore, we present a general heterogeneous palmprint discriminative feature learning model to make the proposed method suitable for multiple heterogeneous palmprint recognition. Experimental results on the widely used PolyU multispectral palmprint database clearly demonstrate the effectiveness of the proposed method.Recently-emerged haptic guidance systems have a potential to facilitate the acquisition of handwriting skills in both adults and children. In this paper we present a longitudinal experimental study that examined the effects of haptic guidance to improve handwriting skills in children with learning difficulties. A haptic-based handwriting training platform that provides haptic guidance along the trajectory of a handwriting task was utilized. 12 children with mild intellectual difficulty, experiencing challenges in manipulating the visual information to control a pincer grip, participated in the study. Children were divided into two groups, a target group and a control group. The target group completed haptic-guided training and pencil-and-paper test whereas the control group took only the pencil-and-paper test without any training. A total of 32 handwriting tasks was used in the study where 16 tasks were used for training while the entire 32 tasks were completed for evaluation. Results demonstrated that the target group performed significantly better than the control group for handwriting tasks that are visually familiar but haptically difficult (Wilcoxon signed-rank test, p less then 0.01). An improvement was also seen in the performance of untrained tasks as well as trained tasks (Spearman’s linear correlation coefficient, 0.667; p=0.05).COVID-19 is a life threatening disease which has a enormous global impact. As the cause of the disease is a novel coronavirus whose gene information is unknown, drugs and vaccines are yet to be found. For the present situation, disease spread analysis and prediction with the help of mathematical and data driven model will be of great help to initiate prevention and control action, namely lockdown and qurantine. There are various mathematical and machine-learning models proposed for analyzing the spread and prediction. Each model has its own limitations and advantages for a particluar scenario. This article reviews the state-of-the art mathematical models for COVID-19, including compartment models, statistical models and machine learning models to provide more insight, so that an appropriate model can be well adopted for the disease spread analysis. Furthermore, accurate diagnose of COVID-19 is another essential process to identify the infected person and control further spreading. As the spreading is fast, there is a need for quick auotomated diagnosis mechanism to handle large population. Deep-learning and machine-learning based diagnostic mechanism will be more appropriate for this purpose. In this aspect, a comprehensive review on the deep learning models for the diagnosis of the disease is also provided in this article.Researchers have developed a computational field called virtual screening (VS) to aid experimental drug development. These methods utilize experimentally validated biological interaction information to generate datasets and use the physicochemical and structural properties of compounds and target proteins as input information to train computational prediction models. At present, deep learning has been used in the field of biomedicine widely, and the prediction of CPRs based on deep learning has developed rapidly and has achieved good results. The purpose of this study is to investigate and discuss the latest applications of deep learning techniques in CPR prediction. First, we describe the datasets and feature engineering (i.e., compound and protein representations and descriptors) commonly used in CPR prediction methods. Then, we review and classify recent deep learning approaches in CPR prediction. Next, a comprehensive comparison is performed to demonstrate the prediction performance of representative methods on classical datasets.