Rivas McKenna

The effects of five major determinants varied geographically and were significantly stronger among neighborhoods with high prevalence of stroke. Highly flexible machine learning identifies true drivers of neighborhood cardiovascular health outcomes from wide-ranging information in an agnostic and reproducible way. The identified major determinants…[Read more]

Based on its promising beneficial effects in underlying complications of COVID-19, sivelestat could be considered as a promising modality for better management of COVID-19-induced ALI/ARDS or coagulopathy.

To investigate the origins of age-related decreases in axial length in the literature.

A literature review was performed, including…[Read more]

and contour mandibular asymmetries in patients under 7 years of age.

The purpose of this study was to compare the maxillary mesiodistal dental angulations of Class II malocclusion patients treated with the Jones Jig, followed by fixed appliances, with normal values of a historical control group, on panoramic radiographs.

The sample…[Read more]

Silicon photonics coherent transceivers have integrated all the necessary optics except the lasers. The laser source has become a major obstacle to further reduce the cost, footprint, power consumption of the coherent transceivers for short-reach optical interconnects. One solution is to utilize remotely delivered local oscillator (LO) from the…[Read more]

0% frequency, discrepancies were found in only 5 genes from 4 patients, suggesting comparability of the TPS to WES in practical laboratory settings. We provide the unbiased genetic landscape that might contribute to MCL pathogenesis and recurrent genes conferring unfavourable outcomes.Immunoassays based on sandwich immuno-complexes of capture and…[Read more]

Owing to the universality of Wigner random matrices, our results on the spectral properties of random graphs hold for general classes of random matrices that are ubiquitous in several areas of physics. In particular, our results could lead to novel insights into the equilibration times of isolated quantum systems defined by random Hamiltonians, a…[Read more]

87-6.10) μmol/L and the reference interval 1.28-19.67 μmol/L (2.5th-97.5th percentile). In women median TMAO plasma concentration was 3.56 (Q1-Q3 2.41-5.15) μmol/L and the reference interval 1.08-17.12 μmol/L. In multivariable regression analysis plasma TMAO was associated with sex, renal function and diet. The association of TMAO and diet was sig…[Read more]

Continuous positive airway pressure (CPAP) is the primary treatment of obstructive sleep apnea/hypopnea syndrome (OSA). Most sleep physicians are in agreement that a certain number of OSA patients cannot or will not use CPAP. Although other conservative therapies such as oral appliance, sleep hygiene and sleep positioning may help some of these…[Read more]

Herein we briefly review the in vitro prediction methods that serve to identify drugs with a potential to induce hyperbilirubinemia. In vitro assays can be deployed early in drug development and may help to minimize late-stage attrition. Based on current evidence, drugs that behave as mono- or multispecific inhibitors of OATP1B1, UGT1A1, and BSEP…[Read more]

Extramammary Paget’s disease (EMPD) is a rare skin cancer that frequently occurs in the anogenital region in the elderly. Prognosis in patients with metastatic EMPD is poor as EMPD treatment has advanced little in recent years, primarily because no EMPD cell line has been established.

We aimed to establish an ex vivo EMPD disease model…[Read more]

Chronic alcoholism (CA) decreases bone mass and increases the risk of hip fracture. Alcohol and its main metabolite, acetaldehyde impairs osteoblastogenesis by increasing oxidative stress. Aldehyde dehydrogenase (ALDH) is the rate-limiting enzyme in clearing acetaldehyde from the body. The clinical relevance of ALDH in skeletal function has been…[Read more]

The final version of the developed scale encompassed 27 items, within three domains, including knowledge (regarding nutritional care), assessment and evidence utilization, and care delivery. The scale exhibited evidence of face and content validity, adequate construct and concurrent validity, and good internal consistency.

This study…[Read more]

Health risks due to particulate matter (PM) from wildfires may differ from risk due to PM from other sources. In places frequently subjected to wildfire smoke, such as Reno, Nevada, it is critical to determine whether wildfire PM poses unique risks. Our goal was to quantify the difference in the association of adverse asthma events with PM on days…[Read more]

Older adults also relied more on harness assistance during balance recovery. Exaggerated arm and trunk responses to sudden lateral balance perturbations in older adults appear to influence step type and balance recovery. Associations of these persistently amplified movements with an increased reliance on harness assistance suggest that training to…[Read more]

Digital nature can provide a substitute for real nature for those who have limited access to green space, or are confined to their homes, for example during the worldwide COVID-19 lockdown. In a large-scale online survey, respondents (N = 1203) watched videos of digital nature, varying in terms of type of nature (wild versus tended nature) and…[Read more]

Five Ib-type cyclopeptide alkaloids, jubanines F-J (1-5), and three known compounds, nummularine B (6), daechuine-S3 (7), and mucronine K (8) were isolated from the roots of Ziziphus jujuba. Their structures were fully characterized by spectroscopic analyses in combination with chemical derivatization. Compounds 1-3, and 6 were evaluated for their…[Read more]

This report paves a new avenue for synthesizing AuNCs based on either the bottom-up reduction or top-down etching method, establishing real-time fluorescence assays for ACP by means of PPi as the substrate, and further exploring the sensing applications of fluorescent AuNCs.It is rare for studies to approach psychosocial outcomes of childhood…[Read more]

TACC3 contributes to gastric tumorigenesis by promoting EMT via the ERK/Akt/cyclin D1 signaling pathway. The correlation between TACC3 expression and multiple clinicopathological variables implies that its effective therapeutic targeting in GC will depend on the tumor subtype.

Cervical cancer (CC) is one of the leading causes of mortality…[Read more]

The β-Lg dimers also resulted in the undetectable human IgE-binding.Goat and second cheese whey from sheep’s milk are by-products of the manufacture of goat cheeses and whey cheeses from sheep. Due to their composition which, apart from water-about 92%-includes lactose, proteins, fat, and minerals, and the elevated volumes generated, these…[Read more]

The purpose of the presented research is estimation of the performance characteristics of the economic total-body Jagiellonian-PET system (TB-J-PET) constructed from plastic scintillators. The characteristics are estimated according to the NEMA NU-2-2018 standards utilizing the GATE package. The simulated detector consists of 24 modules, each…[Read more]