Dennis Kondrup

Our findings indicate that DNA strand breaks, which are usually considered to pose a severe threat to cells, trigger cellular reprogramming towards stem cells via the activity of ATR and STEMINs.The expansion of gene families during evolution, which can generate functional overlap or specialization among their members, is a characteristic feature…[Read more]

The mean age and BMI were 54.6 ± 14.6 years and 30.1 ± 4.1 kg/m2, respectively. The mean preoperative DeMeester score was 43.1 ± 36.1, LES pressure was 19.9 ± 18.4 mmHg, and acid exposure time was 11.4 ± 9.6. Mean GERD-HRQL scores decreased from 27.3 ± 9.2 preoperative to 5.3 ± 4.5 postoperative; P less then .0001. Preoperative GERD-HRQL scores…[Read more]

Although most of the studies reported positive health effects in athletes and active individuals, there is still no substantial scientific evidence to suggest that probiotics, prebiotics and synbiotics play an important role in improving an athlete´s performance. These studies are currently limited in number and quality, hence it is necessary to…[Read more]

The neuroinflammatory signature that accompanies mild TBI in older adults differs from that of younger adults. The differences seen are notable for their roles in neutrophil attraction (IL-8), neuronal-microglial-immune cell interactions (fractalkine), and chronic inflammation (IL-6).

The neuroinflammatory signature that accompanies mild TBI in…[Read more]

The cumulative temperature method could be used to predict the start and end dates of the monoterpene emissions. To estimate the annual monoterpene emissions, a temperature and light intensity dependent emission model was modified to incorporate the effect of growth temperature on seasonal patterns of Ms. Annual monoterpene emissions were found to…[Read more]

The identification of underlying mechanisms for MSC-EVs regulation on impaired diabetic wound healing might provide a new direction for MSC-centered treatment for diabetic lower limb ischemia and ulcers. Immunomodulatory and angiogenic effects of MSC-derived extracellular vesicles on diabetic foot ulcer.

To investigate the associations of…[Read more]

The promising result demonstrated in this work has shown great potential to employ the robust mini-SLidar system for atmospheric monitoring in the boundary layer.We experimentally demonstrate a harmonic-order controllable L-band Er-doped passively mode-locked fiber laser based on nonlinear polarization rotation (NPR). Distinct from all previous…[Read more]

The trained classifier was tested on the data of 14 boys and 7 girls with ASD and 14 TD boys and 7 TD girls. The sensitivity, specificity, and precision of the proposed approach for boys were 85.71%, 100%, and 92.85%, respectively. These measures were 71.42%, 100%, and 85.71% for girls, respectively. It was shown that the proposed approach…[Read more]

Products used most frequently to decontaminate burn patients included water (100%) followed by soap (44%).

This pilot survey of level I and II trauma centers in the state of Michigan revealed variability in the use of burn patient decontamination protocols and consistency of use. Additional research is warranted to determine if our results…[Read more]

We argue that an analysis of popular media can provide valuable insights into how everyday experiences of safety, risk and wellbeing are being shaped and contested with dating and hookup app use, and that these insights can be used to develop meaningful health promotion strategies.Genital fashioning practices, such as Brazilian waxing and female…[Read more]

Myo-inositol and its derivatives play vital roles in plant stress tolerance. Myo-inositol-1-phosphate synthase (MIPS) is the rate-limiting enzyme of myo-inositol biosynthesis. However, the role of apple MIPS-mediated myo-inositol biosynthesis in stress tolerance remains elusive. In this study, we found that ectopic expression of MdMIPS1 from apple…[Read more]

011, 95% CI, 0.6-4.7%). see more In the CT group, univariate analyses demonstrated a significant effect of age on the aspect of occipital condyles (P = .016). Horses with regular occipital condyles were older (median age = 881 days; interquartile range = 1054) than horses with a defect (median age = 109 days, interquartile range = 318). All horses…[Read more]

To determine the outcomes after mechanical thrombectomy (MT) versus medical management in patients with minor stroke symptomatology.

A meta-analysis was performed for studies reporting outcomes after MT, either as stand-alone therapy or with intravenous thrombolysis in patients with minor stroke and large-vessel occlusion.

Fourteen…[Read more]

Furthermore, glycyrrhizic acid attenuated OGD/R-induced impairment of astrocytic glutamate clearance mediated by the HMGB1-TLR4 axis. (4) Conclusion The HMGB1/TLR4 axis is a potential target for the treatment of post-ischemic excitotoxicity caused by GLAST dysfunction in astrocytes.(1) Background PRAME, NY-ESO-1, and SSX2 are cancer testis…[Read more]

One of the most severe complications of auricular reconstruction for microtia is exposure of the cartilage framework. Recently, negative pressure wound therapy (NPWT) has become popular for a variety of complex wounds but reports on methods for microtia reconstruction are scarce. Thus, we aimed to detail the use of NPWT for cartilage exposure in…[Read more]

Focused on compassionate patient care, Dr. Goske’s overarching goal was to improve the patient experience throughout the many advancements in radiology. Her excellence in patient care, innovative approaches to education and safety, and collaborative ability to bring out the best in radiology led to her being the 2018 recipient of the ACR Gold…[Read more]

The key step for Cl(-I) removal was identified as the formation of ·Cl or ·Cl2- from the oxidation of Cl(-I) by ·SO4- and ·OH, and their contribution ratios were estimated to be 67.4% and 32.6%, respectively.Gold is one of the potential toxic heavy metals. In the present study, Au3+ was detected and removed by newly-designed fluorescent mic…[Read more]

Bleach was the only cleaning agent associated with a respiratory symptom tightness in the chest (unadjusted OR = 2.46; 95% CI 1.01-6.89) but statistical significance did not persist after adjustment for age and sex. Hand dermatitis was associated with actual disinfecting tasks (adjusted OR = 2.19; 95% CI 1.10-4.66). Bleach was the only cleanin…[Read more]

Thoracofemoral bypass (TFB) has been used infrequently but is an alternative for select patients with aortoiliac occlusive disease. Limited data are available in the reported data regarding TFB, with all studies small, single-center series. Selleckchem Docetaxel We aimed to describe the perioperative and long-term survival, patency, and rate of…[Read more]

Pulmonary arterial hypertension (PAH) is a devastating complication of Systemic Sclerosis (SSc). Screening for PAH in SSc has increased detection, allowed early treatment for PAH, and improved patient outcomes. Blood-based biomarkers that reliably identify SSc patients at risk of PAH, or with early disease, would significantly improve screening,…[Read more]